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Published on: July 21, 2023
Salmonella Bacteremia Causing Mycotic Pseudoaneurysm of Right Common Iliac Artery Complicated by Septic Caval
Sinduja Sivaramalingam1, Dillibabu Ethiraj2, Sripriya Srinivas1
1Department of Radiology, Dr. Rela Institute and Medical Centre, Chennai, Tamil Nadu, India.
Abstract:
Mycotic pseudoaneurysm (MPA) is a blind, saccular outpouching of the arterial lumen of infective origin. MPA is a rare life-threatening condition and if not treated early, has a 67% mortality rate due to sepsis and hemorrhage. Major predisposing factors are diabetes mellitus, chronic renal failure, malignancy, steroids, and intravenous drug use. Imaging modalities include Doppler ultrasound, contrast-enhanced computed tomography, and digital subtraction angiography. We report a unique case of Salmonella bacteremia-related MPA of the right common iliac artery complicated by septic inferior vena cava (IVC) thrombosis in a patient with uncontrolled diabetes. Such transcompartmental involvement of IVC has hitherto not been described in the literature and hence makes for interesting documentation. This case ponders upon the aggressiveness of the invasive nontyphoidal Salmonella infection pathogen and the need for early imaging of suspicious patients to reduce morbidity and mortality.
Insights
Mycotic pseudoaneurysm (MPA), a rare infection of arteries, can be fatal if untreated. This case highlights Salmonella bacteremia causing MPA and IVC thrombosis in a diabetic patient, emphasizing early diagnosis.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Radiology
Background:
- Mycotic pseudoaneurysm (MPA) is a rare but life-threatening arterial infection with a high mortality rate.
- Predisposing factors include diabetes, renal failure, malignancy, steroid use, and IV drug use.
Observation:
- A unique case of Salmonella bacteremia-related MPA of the right common iliac artery is presented.
- The MPA was complicated by septic inferior vena cava (IVC) thrombosis, a previously undescribed transcompartmental involvement.
Findings:
- The case demonstrates the aggressive nature of invasive nontyphoidal Salmonella infections.
- Uncontrolled diabetes was a significant comorbidity in this patient.
Implications:
- Early imaging is crucial for diagnosing suspicious cases of MPA to reduce morbidity and mortality.
- This case underscores the importance of considering invasive bacterial infections in patients with vascular complications.
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