Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Aug 27, 2025

Micro-scale Engineering for Cell Biology

Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

Engineering multicellular living systems-a Keystone Symposia report.

Jennifer Cable¹, Paola Arlotta^2,3, Kevin Kit Parker^4,5

¹PhD Science Writer, New York, New York, USA.

Annals of the New York Academy of Sciences

|September 30, 2022

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Generation of a STRAIGHT-IN Dual AAVS1 hiPSC line with orthogonal landing pads for versatile DNA payload integration.

Stem cell research·2026

Same author

Expansion Revealing of Pathology Resolves Nanostructures Associated with Inflammatory Phenotypes in COVID-19 Decedent Human Brain Tissue.

bioRxiv : the preprint server for biology·2026

Same author

Cardiomyopathy phenotypes caused by a heterozygous MYBPC3 mutation revealed in different hiPSC cardiac models.

Experimental cell research·2026

Same author

In vitro modeling of renal injury-induced cardiac effects using human iPSC-derived organoids.

Cell communication and signaling : CCS·2026

Same author

Gene syntax defines supercoiling-mediated transcriptional feedback.

Science (New York, N.Y.)·2026

Same author

STRAIGHT-IN Dual: a platform for dual single-copy integrations of DNA payloads and gene circuits into human induced pluripotent stem cells.

Nature biomedical engineering·2026

Same journal

Multiomics Profiling During Autoimmune Demyelination Highlights a Complex Regulatory Role for Ataxin-1 in B Cells.

Annals of the New York Academy of Sciences·2026

Same journal

Global Trends in Light Pollution and Their Relationship With Socioeconomic Factors.

Annals of the New York Academy of Sciences·2026

Same journal

Wired for Corruption: Inter-Brain Synchrony Encodes Bribery-Related Value Information and Predicts Bribery Agreement.

Annals of the New York Academy of Sciences·2026

Same journal

LM-YOLO: A Lightweight Multi-Scale Enhanced Model for Forest Smoke Detection Using Unmanned Aerial Vehicles.

Annals of the New York Academy of Sciences·2026

Same journal

Polyrhythm Perception and Production: A Scoping Review.

Annals of the New York Academy of Sciences·2026

Same journal

DARTS-CNN-BiLSTM: Intelligent Fault Diagnosis for Computer Numerical Control Machine Tool Feed System.

Annals of the New York Academy of Sciences·2026

See all related articles

Summary

This summary is machine-generated.

Engineering multicellular living systems offers insights into biology and disease. Experts convened to discuss advances in understanding cell cooperation and engineering systems like organoids and organ-on-a-chip models.

Area of Science:

Biotechnology
Systems Biology
Bioengineering

Background:

Engineering complex multicellular systems holds significant promise for understanding biological processes and diseases.
Advancements in this field are crucial for revolutionizing drug development.
Understanding cellular communication and environmental interactions is key to coordinating multicellular systems.

Purpose of the Study:

To discuss recent advances in engineering multicellular living systems.
To explore how cells cooperate within multicellular systems.
To highlight efforts in creating engineered systems such as organoids and organ-on-a-chip models.

Main Methods:

Expert discussions at the Keystone symposium "Engineering Multicellular Living Systems".

Keywords:

computational engineered living engineered organs multicellular systems

More Related Videos

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System

Published on: December 23, 2022

Simple, Affordable, and Modular Patterning of Cells using DNA

Simple, Affordable, and Modular Patterning of Cells using DNA

Published on: February 24, 2021

Related Experiment Videos

Last Updated: Aug 27, 2025

Micro-scale Engineering for Cell Biology

Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System

Published on: December 23, 2022

Simple, Affordable, and Modular Patterning of Cells using DNA

Simple, Affordable, and Modular Patterning of Cells using DNA

Published on: February 24, 2021

Concurrent symposium on "Organoids as Tools for Fundamental Discovery and Translation" facilitated cross-disciplinary insights.

Review of current research in cellular cooperation and engineered biological systems.

Main Results:

Shared understanding of biochemical, mechanical, and environmental cues governing cell interactions.
Progress in developing novel engineered systems like organoids and organ-on-a-chip.
Identification of common themes and synergies between multicellular systems engineering and organoid research.

Conclusions:

Engineering multicellular systems requires a deep understanding of cell-cell and cell-environment interactions.
Organoids and organ-on-a-chip models represent significant progress in emulating biological functions.
Interdisciplinary collaboration is vital for advancing the field of engineered living systems.