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Mixed Reality Assisted Radical Endoscopic Thyroidectomy
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379
Time to Symptom Resolution After Total Thyroidectomy for Graves' Disease
Andrea Gillis1, Ruth Obiarinze2, M Chandler McLeod1
1Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.
The Journal of Surgical Research
|September 30, 2022
Summary
Total thyroidectomy (TT) offers rapid symptom relief for Graves' disease patients. Most common symptoms, like fatigue and heat intolerance, significantly improve within weeks after the procedure.
Area of Science:
- Endocrinology
- Surgical Oncology
Background:
- Total thyroidectomy (TT) is a recognized treatment for Graves' disease.
- The timeline for symptom resolution post-TT for Graves' disease requires definition.
Purpose of the Study:
- To prospectively evaluate the time course of symptom improvement after total thyroidectomy in patients with Graves' disease.
Main Methods:
- Prospective survey data collection from 79 patients undergoing TT for Graves' disease (2019-2021).
- Patients completed surveys preoperatively and at 2 weeks, then monthly postoperatively.
- Kaplan-Meier analysis was used to determine symptom recovery time.
Main Results:
- 50 patients completed follow-up (63% response rate); average age 38, 88% female.
- Rapid symptom resolution observed for tremor, diarrhea, and palpitations (median 1 week).
- Eye symptoms, heat/cold intolerance, memory deficits, and fatigue resolved within a median of 3 weeks.
Conclusions:
- Graves' disease symptoms significantly improve shortly after total thyroidectomy.
- A median symptom improvement time of less than one month was observed post-TT.
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