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Updated: Aug 27, 2025

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The tumor mycobiome: A paradigm shift in cancer pathogenesis
1Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY 10010, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA; Department of Urology, NYU Grossman School of Medicine, New York, NY 10016, USA.
Abstract:
Distinct fungal communities or "mycobiomes" have been found in individual tumor types and are known to contribute to carcinogenesis. Two new studies present a comprehensive picture of the tumor-associated mycobiomes from a variety of human cancers. These studies reveal that fungi, although in low abundance, are ubiquitous across all major human cancers and that specific mycobiome types can be predictive of survival.
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