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A replication study of NMDA receptor agonism sufficiency to enhance 10-Hz rTMS-induced motor cortex plasticity

Jamie Kweon1, Megan Vigne1, Rich Jones2

  • 1Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Butler Hospital, Providence, RI, USA.

Brain Stimulation
|September 30, 2022
PubMed
Abstract

No abstract available in PubMed .

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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.