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Radiochemical In Situ Hybridization in Developmental Studies of the Pineal Gland

Martin Fredensborg Rath1, Morten Møller2

  • 1Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark. mrath@sund.ku.dk.

Methods in Molecular Biology (Clifton, N.J.)
|September 30, 2022
PubMed

Keywords:
Brain developmentIn situ hybridizationPineal glandRadioactiveRodent

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In-situ Hybridization

In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
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