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Updated: Aug 19, 2026

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
Published on: December 2, 2015
[AMDP profile of endogenous and non-endogenous depressions]
Abstract:
The multifactorial, comprehensive description--as allowed by the AMDP scales--of two samples of depressed patients (95 endogenous vs. 86 nonendogenous according to ICD-9) illustrates a common pattern dominated by anxiety, depression, retardation and hostility but also significant differences: endogenous depressives reach higher Depression and Apathy-Retardation scores, whereas nonendogenous depressives have higher Dramatization and Hostility scores. The methodological aspects linked to the extraction of factorial profiles and the implications of the endogenous/nonendogenous differences are discussed.
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