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Updated: Aug 27, 2025

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM
Published on: August 5, 2009
Tracking moving objects through scattering media via speckle correlations
Y Jauregui-Sánchez1, H Penketh2, J Bertolotti2
1Physics and Astronomy Department, University of Exeter, Stocker Road, Exeter, EX4 4QL, UK. y.jauregui-sanchez@exeter.ac.uk.
Abstract:
Scattering can rapidly degrade our ability to form an optical image, to the point where only speckle-like patterns can be measured. Truly non-invasive imaging through a strongly scattering obstacle is difficult, and usually reliant on a computationally intensive numerical reconstruction. In this work we show that, by combining the cross-correlations of the measured speckle pattern at different times, it is possible to track a moving object with minimal computational effort and over a large field of view.
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