Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Exosomes01:36

Overview of Exosomes

2.8K
Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
2.8K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

2.7K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Human-Relevant In Vitro Skin Models: From Regulatory-Validated Platforms to Emerging Technologies for Translational Dermatology.

Experimental dermatology·2026
Same author

Topical Application of Probiotic-Derived EGF From <i>Pediococcus pentosaceus</i> Improves UVB-Induced Photoaging in Hairless Mice.

Annals of dermatology·2026
Same author

A Split-Scar Study: Study of Surgical Scar Using Exosomes.

Journal of cosmetic dermatology·2026
Same author

A Pilot Study on the Use of Topical Gold and Diamond Suspension Combined With 1,064 nm Picosecond Nd:YAG Laser for the Treatment of Facial Melasma.

Annals of dermatology·2026
Same author

Efficacy and Safety of Novel Botulinum Toxin Type A (Protoxin) in the Treatment of Moderate to Severe Glabellar Lines: A Multicenter, Randomized, Double-Blind, Active-Controlled Phase III Study.

Annals of dermatology·2026
Same author

Author Correction: A virtual memory CD8+ T cell-originated subset causes alopecia areata through innate-like cytotoxicity.

Nature immunology·2025

Related Experiment Video

Updated: Aug 27, 2025

Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes
09:30

Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes

Published on: May 24, 2019

7.5K

Exosomes as novel player in dermatologic field.

Su Jung Park1, Sun Hye Shin2, Ka Ram Kim2

  • 1Department of Dermatology, Chungnam National University Sejong Hospital, Sejong, South Korea.

Dermatologic Therapy
|October 1, 2022
PubMed
Summary

Stem cell-derived exosomes show promise for treating skin conditions due to their regenerative and anti-inflammatory properties. This review explores their therapeutic potential and mechanisms in dermatology.

Keywords:
dermatologyexosomestem cell-derived

More Related Videos

Preparation of Exosomes for siRNA Delivery to Cancer Cells
09:59

Preparation of Exosomes for siRNA Delivery to Cancer Cells

Published on: December 5, 2018

25.3K
Isolation and Characterization of Exosomes from Skeletal Muscle Fibroblasts
06:27

Isolation and Characterization of Exosomes from Skeletal Muscle Fibroblasts

Published on: May 16, 2020

3.5K

Related Experiment Videos

Last Updated: Aug 27, 2025

Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes
09:30

Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes

Published on: May 24, 2019

7.5K
Preparation of Exosomes for siRNA Delivery to Cancer Cells
09:59

Preparation of Exosomes for siRNA Delivery to Cancer Cells

Published on: December 5, 2018

25.3K
Isolation and Characterization of Exosomes from Skeletal Muscle Fibroblasts
06:27

Isolation and Characterization of Exosomes from Skeletal Muscle Fibroblasts

Published on: May 16, 2020

3.5K

Area of Science:

  • Cell Biology
  • Dermatology
  • Regenerative Medicine

Background:

  • Exosomes are nano-sized vesicles crucial for intercellular communication.
  • They transfer molecules, influencing target cell functions.
  • Stem cell-derived exosomes exhibit regenerative and anti-inflammatory capacities.

Purpose of the Study:

  • To review recent studies on exosome applications in dermatologic conditions.
  • To elucidate the mechanisms behind exosome therapy in skin diseases.
  • To guide dermatologists in utilizing exosomes for improved treatment strategies.

Main Methods:

  • Literature review of studies on exosome applications in dermatology.
  • Analysis of exosome cargo and their effects on skin cells.
  • Evaluation of therapeutic outcomes in various dermatologic conditions.

Main Results:

  • Exosomes from mesenchymal stem cells, adipose-derived stem cells, and pluripotent stem cells show potential in skin repair.
  • Evidence suggests exosomes modulate inflammatory pathways and promote regeneration.
  • Specific applications include wound healing, anti-aging, and treatment of inflammatory skin disorders.

Conclusions:

  • Stem cell-derived exosomes represent a promising therapeutic approach for dermatologic conditions.
  • Further research into exosome mechanisms will refine clinical applications.
  • Harnessing exosome potential can lead to novel treatment strategies in dermatology.