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Medication adherence to obeticholic acid: a real-world experience using medication event monitoring systems
Pedro Suárez-Artime1, Goretti Durán-Piñeiro1, Marisol Rodríguez-Cobos1
1Pharmacy Department, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela. Spain.. pedro.suarez.artime@sergas.es.
Objective:
We designed a clinical study to analyze patterns of adherence to obeticholic acid, factors influencing the adherence and potential correlation with treatment efficacy by using MEMS® cap in practice daily. Method: A multicenter prospective observational study of patients with primary biliary cholangitis. Adherence will be measured by MEMS® cap, pill count, and patient-reported outcomes during 3 months. The quality of life will be self- reported using the Chronic Liver Disease Questionnaire test, European Quality of Life 5-Dimension Questionnaire test and Itch Severity Scale.
Conclusions:
We expect to clarify if there is correlation between adherence with treatment efficacy and to identify causes for poor compliance and introduce measures to reduce its prevalence.
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