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Related Concept Videos

Infertility in Males01:23

Infertility in Males

319
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
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Spermatogenesis01:41

Spermatogenesis

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Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
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Infertility in Females01:28

Infertility in Females

378
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
378
Menopause01:28

Menopause

235
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
235
In Vitro Fertilization01:24

In Vitro Fertilization

363
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
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Birth Control Methods01:22

Birth Control Methods

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Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
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Updated: Aug 27, 2025

Fertility Preservation in Patients with Severe Ovarian Dysfunction
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[Fertility preservation for transmen].

S Grateau1, C Dupont1, D Rivet-Danon1

  • 1Service de biologie de la reproduction - CECOS, Sorbonne université, hôpital Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France.

Gynecologie, Obstetrique, Fertilite & Senologie
|October 2, 2022
PubMed
Summary
This summary is machine-generated.

Fertility preservation for transgender men undergoing female-to-male transition is crucial. Options like oocyte or ovarian tissue cryopreservation can help safeguard future parenthood despite medical and surgical interventions.

Keywords:
Congélation de tissu ovarienFertility preservationFtMHommes transgenresOocyte vitrificationOvarian tissue freezingPréservation de la fertilitéTransgender malesTransidentityTransidentitéVitrification des ovocytes

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Area of Science:

  • Reproductive Endocrinology
  • Transgender Health
  • Medical Ethics

Context:

  • Medical and legislative advancements enable fertility preservation for transgender individuals.
  • Female-to-male (FtM) transition involves androgen therapy impacting gonadal function and potential surgeries compromising fecundity.
  • Parenthood is a significant consideration for many transgender men.

Purpose:

  • To review current literature on fertility preservation strategies for transgender men.
  • To highlight the importance of addressing fertility concerns during gender transition.
  • To inform clinical practice and future research in this area.

Summary:

  • Androgen therapy during FtM transition can cause reversible ovulation blockage, with long-term effects on fertility and offspring health being largely unknown.
  • Surgical interventions like oophorectomy or hysterectomy permanently impact fertility.
  • Fertility preservation primarily involves oocyte or ovarian tissue cryopreservation for transgender men.

Impact:

  • Increases awareness of fertility preservation needs in transgender men.
  • Supports informed decision-making for individuals considering gender transition.
  • Guides healthcare providers in offering comprehensive reproductive care to transgender patients.