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Updated: Aug 27, 2025

12:03
Fertility Preservation in Patients with Severe Ovarian Dysfunction
Published on: March 25, 2021
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[Fertility preservation for transmen]
S Grateau1, C Dupont1, D Rivet-Danon1
1Service de biologie de la reproduction - CECOS, Sorbonne université, hôpital Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France.
Gynecologie, Obstetrique, Fertilite & Senologie
|October 2, 2022
Summary
Fertility preservation for transgender men undergoing female-to-male transition is crucial. Options like oocyte or ovarian tissue cryopreservation can help safeguard future parenthood despite medical and surgical interventions.
Area of Science:
- Reproductive Endocrinology
- Transgender Health
- Medical Ethics
Context:
- Medical and legislative advancements enable fertility preservation for transgender individuals.
- Female-to-male (FtM) transition involves androgen therapy impacting gonadal function and potential surgeries compromising fecundity.
- Parenthood is a significant consideration for many transgender men.
Purpose:
- To review current literature on fertility preservation strategies for transgender men.
- To highlight the importance of addressing fertility concerns during gender transition.
- To inform clinical practice and future research in this area.
Summary:
- Androgen therapy during FtM transition can cause reversible ovulation blockage, with long-term effects on fertility and offspring health being largely unknown.
- Surgical interventions like oophorectomy or hysterectomy permanently impact fertility.
- Fertility preservation primarily involves oocyte or ovarian tissue cryopreservation for transgender men.
Impact:
- Increases awareness of fertility preservation needs in transgender men.
- Supports informed decision-making for individuals considering gender transition.
- Guides healthcare providers in offering comprehensive reproductive care to transgender patients.
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