Microbial elimination of pyrethroids: specific strains and involved enzymes

Pyrethroids, which are synthetic organic insecticides, are widely used in agriculture and households to resist pests and control disease transmission. However, pyrethroids have inevitably caused environmental pollution, leading to concerns for food safety and human health. Bioremediation has emerged as one of the most promising methods to eliminate pyrethroids compounds. Pyrethroid-degrading microorganisms and the relevant enzymes have shown an efficient ability in degrading pyrethroids by hydrolyzing the ester linkage. In this review, a wide variety of pyrethroid-degrading strains were presented and classified from different sources, such as wastewater, soils, and oceans. In addition, the recombinant expression, enzyme identification, and molecular modification of these microbial pyrethroid-degrading enzymes were also compared and discussed in detail. Moreover, the potential applications of pyrethroid-degrading enzymes, including immobilization and biodegradation towards a series of pyrethroids, were also presented. All of the positive results obtained from this review could be a good guideline for the other research in this field. KEY POINTS: • Distribution of pyrethroid-degrading strains in different sources was summarized. • Enzymatic properties including pH, temperature, and substrate specificity were compared. • Promising molecular modification and immobilization of hydrolases were present.