Imaging of pediatric neuroblastoma: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper

Area of Science:

• Pediatric Oncology
• Diagnostic Imaging
• Radiology

Background:

• Neuroblastoma is the most frequent extracranial solid neoplasm in pediatric patients.
• Accurate diagnosis and staging are critical for effective treatment planning.
• Standardized imaging protocols are needed for consistent patient management.

Purpose of the Study:

• To establish consensus-based imaging recommendations for neuroblastoma.
• To provide guidelines for imaging at diagnosis and during follow-up.
• To improve the quality of care for children with neuroblastoma.

Main Methods:

• A panel of experts convened to develop consensus guidelines.
• Literature review and evidence-based analysis informed the recommendations.
• Recommendations cover imaging modalities and interpretation criteria.

Main Results:

• Consensus was reached on key imaging features for neuroblastoma diagnosis.
• Specific recommendations were formulated for staging and assessing treatment response.
• Guidelines for surveillance imaging during follow-up were established.

Conclusions:

• The developed imaging recommendations provide a standardized approach for pediatric neuroblastoma.
• Implementation of these guidelines is expected to enhance diagnostic accuracy and patient management.
• These consensus-based recommendations serve as a valuable resource for clinicians involved in neuroblastoma care.