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The history of pain measurement in humans and animals

Jeffrey S Mogil1

  • 1Department of Psychology and Anesthesia, McGill University, Montreal, QC, Canada.

Frontiers in Pain Research (Lausanne, Switzerland)
|October 3, 2022
PubMed

Keywords:
acutealgesiometryanimalchronichistoryhuman

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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