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Diet and Vitiligo: The Story So Far
Rajoshee R Dutta1, Tanishq Kumar1, Nishikant Ingole2
1Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Cureus
|October 3, 2022
Summary
Discover how vitamins, minerals, and herbal supplements can aid vitiligo treatment. Nutritional interventions, including vitamin B12, folic acid, zinc, and antioxidants, show promise in repigmentation for this immune-mediated skin disease.
Area of Science:
- Dermatology
- Immunology
- Nutritional Science
Background:
- Vitiligo is an acquired skin pigmentation disorder affecting 0.5-2% globally.
- Treatment challenges drive interest in alternative therapies like nutritional supplementation.
- The role of diet diversity in immune-mediated skin diseases requires further interpretation.
Purpose of the Study:
- To review the function of nutrition in immune-mediated inflammatory skin diseases.
- To discuss recent evidence on supplements for vitiligo treatment.
- To highlight the role of antioxidants and specific nutrients in repigmentation.
Main Methods:
- Narrative review of recent and reliable scientific information.
- Analysis of studies on vitamin, mineral, and herbal supplementation for vitiligo.
- Examination of the impact of nutritional interventions on melanin synthesis and immune response.
Main Results:
- Combination therapy of vitamin B12, folic acid, and sun exposure aids repigmentation.
- Zinc and phenylalanine supplementation show therapeutic effects with topical steroids or UV-B.
- Herbal supplements, rich in antioxidants, contribute to skin repigmentation.
Conclusions:
- Nutrition plays a significant role in managing immune-mediated skin diseases like vitiligo.
- Specific supplements demonstrate potential as adjunctive therapies for vitiligo.
- Further research into dietary interventions can optimize vitiligo treatment strategies.
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