Related Experiment Video
Updated: Aug 27, 2025
06:38
An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
Published on: September 12, 2019
9.0K
Adult diffuse hepatic hemangiomatosis
Neha Bhardwaj1, Mayur Parkhi2, Manish Kumar3
1Post Graduate Institute and Medical Education and Research (PGIMER), Department of Pathology, Chandigarh, India.
Autopsy & Case Reports
|October 3, 2022
Summary
Diffuse hepatic hemangiomatosis (DHH) is a rare liver vascular lesion. This case highlights distinguishing DHH from giant cavernous hemangiomas (GCH) for better patient management and prognosis.
Area of Science:
- Hepatology
- Vascular Lesions
- Surgical Pathology
Background:
- Diffuse hepatic hemangiomatosis (DHH) is a rare liver vascular lesion, with unknown etiology but associated with giant cavernous hemangiomas (GCH).
- Hemangiomas are the most common benign liver tumors, but DHH presents as a diffuse involvement.
Observation:
- A 37-year-old hypothyroid woman presented with abdominal fullness due to multiple liver lesions.
- Contrast-enhanced CT diagnosed these as GCH; surgical enucleation was performed for superficial lesions.
Findings:
- Histopathology revealed GCH with parenchymal replacement and micro-hemangiomas, suggesting DHH.
- Retrospective radiological assessment supported the DHH diagnosis; no extrahepatic lesions were found.
Implications:
- Distinguishing DHH from GCH is crucial for management and prognosis due to potential complications like recurrence and coagulopathy.
- Early and accurate diagnosis of adult DHH is essential for preventing severe outcomes.
