Related Experiment Video

Updated: Aug 27, 2025

Isolation of Cerebral Capillaries from Fresh Human Brain Tissue
06:35

Isolation of Cerebral Capillaries from Fresh Human Brain Tissue

Published on: September 12, 2018

12.8K

Cerebral venous thrombosis in a young asymptomatic COVID-19 patient

Rafael Dias1,2,3, Ricardo Soares Dos Reis1,2, Sara Pereira de Sousa4

  • 1Department of Neurology, Centro Hospitalar Universitário de São João.

Porto Biomedical Journal
|October 3, 2022
PubMed

Insights

Cerebral venous thrombosis (CVT) can occur with asymptomatic SARS-CoV-2 infection. This case highlights a potential link between COVID-19, CVT, and thrombocytopenia, relevant to vaccine discussions.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Hematology

Background:

  • Cerebral venous thrombosis (CVT) is a rare but serious condition.
  • COVID-19 (severe acute respiratory syndrome coronavirus 2) has been linked to thrombotic events.
  • Most reported cases involve symptomatic COVID-19 patients.

Purpose of the Study:

  • To report an unusual case of CVT associated with an asymptomatic SARS-CoV-2 infection.
  • To contribute to the understanding of thrombotic complications of COVID-19.
  • To explore potential parallels between COVID-19-associated CVT and vaccine-associated CVT.

Main Methods:

  • Case report of a patient presenting with CVT.
  • Diagnostic confirmation of past SARS-CoV-2 infection through molecular and serological testing.
  • Assessment of clinical presentation, laboratory findings (including thrombocytopenia), and absence of COVID-19 symptoms.

Main Results:

  • The patient experienced CVT temporally associated with an otherwise asymptomatic SARS-CoV-2 infection.
  • Laboratory tests confirmed a past SARS-CoV-2 infection (>3 weeks prior).
  • The patient presented with thrombocytopenia, similar to some cases of vaccine-associated CVT.

Conclusions:

  • Asymptomatic SARS-CoV-2 infection can be associated with CVT.
  • This case expands the spectrum of thrombotic events linked to COVID-19.
  • The presence of thrombocytopenia in this case may inform discussions on COVID-19 vaccines and CVT risk.

Keywords:
COVID-19SARS-CoV-2asymptomaticcerebral venous thrombosis

More Related Videos

Point of Care Transcranial Color-Coded Duplex Ultrasound of the Middle Cerebral Artery04:01

Point of Care Transcranial Color-Coded Duplex Ultrasound of the Middle Cerebral Artery

Published on: August 9, 2024

902
Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound10:41

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound

Published on: June 3, 2021

3.7K

Related Concept Videos

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
28
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
36
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
18
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
19
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
35
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
19