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Related Experiment Videos

A gravimetric technique for evaluating flow continuity from two infusion devices.

R D Leff, W R True, R J Roberts

    American Journal of Hospital Pharmacy
    |June 1, 1987
    PubMed
    Summary

    A new computerized gravimetric technique precisely measures infusion device flow continuity. This method revealed significant differences in flow consistency between peristaltic and piston pumps, highlighting the need for clinical acceptability studies.

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    Area of Science:

    • Biomedical Engineering
    • Medical Device Technology

    Background:

    • Accurate drug delivery relies on consistent infusion device performance.
    • Variations in infusion pump flow can impact patient safety and therapeutic efficacy.

    Purpose of the Study:

    • To develop and validate a computerized gravimetric technique for assessing infusion device flow continuity.
    • To compare the flow continuity of peristaltic and piston-type infusion pumps using the developed technique.

    Main Methods:

    • A BASIC program interfaced with a gravimetric balance and IBM PC recorded serial weight measurements.
    • Effused fluid weight was plotted against time to analyze flow profiles.
    • Two infusion devices (peristaltic and piston) were tested using intravenous solutions at a set rate.

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    Main Results:

    • The gravimetric technique quantitatively depicted flow continuity differences between pump types.
    • The piston-type pump exhibited a significant decrease in flow during its refill cycle (0.007 g/10 sec).
    • The peristaltic pump demonstrated superior flow continuity, with a mean effusion weight closer to the desired rate (0.028 g/10 sec).

    Conclusions:

    • The developed gravimetric technique effectively evaluates infusion device effusion profiles.
    • Peristaltic pumps offer greater flow continuity compared to piston-type pumps.
    • Further research is required to establish clinically acceptable flow continuity standards for infusion devices.