Transcatheter tricuspid valve interventions: Current status and future perspectives

Area of Science:

• Cardiology
• Interventional Cardiology
• Cardiac Surgery

Background:

• Tricuspid regurgitation (TR) is a prevalent valvular heart disease with poor prognosis, often leading to right ventricular heart failure.
• Current surgical interventions for TR carry high mortality risks and are frequently unsuitable for patients with significant comorbidities.
• The limitations of surgical treatment highlight the need for less invasive therapeutic alternatives.

Purpose of the Study:

• To provide a comprehensive overview of transcatheter therapeutic options for chronic tricuspid regurgitation.
• To summarize the technical features of currently available and investigational transcatheter systems for TR.
• To present updated clinical evidence on the efficacy and safety of these evolving percutaneous techniques.

Main Methods:

• Review of existing literature on transcatheter tricuspid valve interventions.
• Analysis of technical aspects of various transcatheter systems (e.g., annuloplasty, valve replacement).
• Synthesis of current clinical data, including procedural outcomes and patient follow-up.

Main Results:

• Several transcatheter systems are in clinical use or evaluation for TR, offering diverse mechanisms of action.
• Early evidence suggests feasibility and potential efficacy of these minimally invasive approaches.
• The field is rapidly evolving, with ongoing research to refine techniques and expand treatment options.

Conclusions:

• Transcatheter therapies represent a significant advancement in managing chronic tricuspid regurgitation.
• These novel approaches offer a promising alternative for patients with high surgical risk.
• Further research and clinical data are essential to establish the long-term role of transcatheter interventions in TR management.