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A case series of eosinophilic myocarditis: different faces of the same coin

Bethlehem Mengesha1, Karen Meir2, Alexander Gural3

  • 1Heart Institute, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.

European Heart Journal. Case Reports
|October 3, 2022
PubMed
Abstract

Insights

Eosinophilic myocarditis (EM) is a rare, life-threatening heart condition. Early diagnosis using imaging and biopsy is crucial to prevent irreversible damage.

Area of Science:

  • Cardiology
  • Pathology

Background:

  • Eosinophilic myocarditis (EM) is a rare cardiac condition with diverse causes and severe outcomes if not promptly diagnosed and managed.
  • It presents a diagnostic challenge due to varied clinical presentations.

Observation:

  • This report details three cases of EM at different disease stages, showcasing distinct clinical manifestations.
  • The diagnostic pathway, emphasizing multimodality imaging and endomyocardial biopsy (EMB), is presented.

Findings:

  • EM is frequently underdiagnosed and poses a significant risk to life.
  • A high index of clinical suspicion is warranted in patients presenting with cardiovascular symptoms and hypereosinophilia, or vice versa.

Implications:

  • Timely identification of EM through multimodality imaging and EMB is critical.
  • Delayed treatment can lead to irreversible myocardial fibrosis, underscoring the urgency of early intervention.
Keywords:
Case seriesEosinophilic myocarditisHeart failureHypereosinophilia

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