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Updated: Jul 2, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
[Pulmonary tuberculosis presenting as a lung mass in children: case report]
M Sol Fernández Sardá1, Lourdes Baez Mellid2, Yaritza Cantillo2
1Servicio de Neumonología, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina. mariasolfs@gmail.com.
Pediatric tuberculosis can rarely present as a lung mass, known as tuberculoma. This case highlights an unusual presentation of tuberculosis in a child, emphasizing the need for considering this diagnosis in persistent lung abnormalities.
Area of Science:
- Pediatric Pulmonology
- Infectious Diseases
- Radiology
Background:
- Tuberculosis (TB) is a leading infectious cause of death globally.
- Pulmonary involvement is common in TB, but tuberculoma is a rare manifestation.
- Early diagnosis and treatment are crucial for favorable outcomes in pediatric TB.
Observation:
- A 15-month-old girl presented with persistent fever, poor weight gain, and a lung abnormality on chest x-ray.
- Contact with a symptomatic individual and a positive tuberculin skin test (TST) were noted.
- Chest CT revealed a bulky left upper lobe mass, initially unresponsive to antibiotics.
Findings:
- Exploratory thoracoscopy and lung biopsy confirmed Mycobacterium tuberculosis.
- The diagnosis of pulmonary tuberculoma as a primary manifestation of TB was established.
- Standard anti-tuberculosis therapy led to a favorable clinical evolution.
Implications:
- This case underscores the importance of considering atypical presentations of tuberculosis in children.
- Pulmonary tuberculoma should be included in the differential diagnosis for pediatric lung masses.
- Prompt microbiological confirmation and appropriate treatment are vital for managing pediatric TB effectively.
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