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A (Controlled) Spill of IL2 for Localized Treatment of Mesothelioma
Rohan Palanki1,2, Kelsey L Swingle1, Michael J Mitchell1,3,4,5,6
1Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania.
Abstract:
A microencapsulated, cell-based IL2 cytokine factory was recently developed, and the safety and efficacy of this platform in a mouse model of mesothelioma were demonstrated. This platform has the potential to overcome current challenges in the delivery of therapeutic cytokines for cancer immunotherapy. See related article by Nash et al., p. 5121.
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