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Post-Intensive Care Syndrome Prevalence Six Months after Critical Covid-19: Comparison between First and Second Waves

Amandine Rapin1, François Constant Boyer2, Bruno Mourvillier3

  • 1Centre Hospitalo-Universitaire de Reims (CHU), Hôpital Sébastopol, Département de Médecine Physique et de Réadaptation, Reims, France; Université de Reims Champagne-Ardenne, Faculté de Médecine, Vieillissement, Fragilité (VieFra) Reims, France. arapin@chu-reims.fr.

Journal of Rehabilitation Medicine
|October 4, 2022
PubMed

Insights

Improved intensive care for COVID-19 survivors did not reduce post-intensive care syndrome (PICS) prevalence. Approximately half of patients experienced PICS, with female sex and diabetes being risk factors.

Area of Science:

  • Critical Care Medicine
  • Infectious Diseases
  • Neurology

Background:

  • Post-intensive care syndrome (PICS) is a significant concern for COVID-19 survivors.
  • Intensive care unit (ICU) management for COVID-19 has evolved since the pandemic's onset.

Purpose of the Study:

  • To investigate the effect of enhanced ICU care on PICS prevalence in COVID-19 patients.
  • To identify risk factors associated with PICS in this population.

Main Methods:

  • Ambispective cohort study of COVID-19 patients from two pandemic waves.
  • PICS assessment at 6 months post-infection using physical (1STS), cognitive (SDMT), and mental health (HADS) measures.

Main Results:

  • No significant difference in PICS prevalence (approx. 52%) between the first and second waves.
  • Improved ICU care (shorter intubation and ICU stay) in the second wave did not decrease PICS rates.
  • Female sex and diabetes mellitus were independently associated with PICS.

Conclusions:

  • Around half of COVID-19 survivors develop PICS, impacting quality of life.
  • Enhanced ICU care did not mitigate PICS; targeted risk identification is crucial.
  • Further research into PICS mechanisms and rehabilitation strategies is needed.
Abstract

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