Related Experiment Video
Updated: Aug 26, 2025

QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii
Published on: June 22, 2017
statgenMPP: an R package implementing an IBD-based mixed model approach for QTL mapping in a wide range of
Wenhao Li1, Martin P Boer1, Bart-Jan van Rossum1
1Biometris, Wageningen University and Research Center, Wageningen, 6700 AC, The Netherlands.
Motivation:
Multi-parent populations (MPPs) are popular for QTL mapping because they combine wide genetic diversity in parents with easy control of population structure, but a limited number of software tools for QTL mapping are specifically developed for general MPP designs.
Results:
We developed an R package called statgenMPP, adopting a unified identity-by-descent (IBD)-based mixed model approach for QTL analysis in MPPs. The package offers easy-to-use functionalities of IBD calculations, mixed model solutions and visualizations for QTL mapping in a wide range of MPP designs, including diallele, nested-association mapping populations, multi-parent advanced genetic inter-cross populations and other complicated MPPs with known crossing schemes.
Availability And Implementation:
The R package statgenMPP is open-source and freely available on CRAN at https://CRAN.R-project.org/package=statgenMPP.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
More Related Videos
Related Concept Videos
Incomplete Dominance
Mechanistic Models: Compartment Models in Individual and Population Analysis
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Pedigree Analysis

