New Technologies to Diagnose and Treat a Multidrug-Resistant Candida auris: A Patent Review

Luana Rossato1, Simone Simionatto2, Mairim Russo Serafini3

  • 1Universidade Federal da Grande Dourados-UFGD, Dourados, Mato Grosso do Sul, Brazil. luanarossato@ufgd.edu.br.

Mycopathologia
|October 4, 2022
PubMed

Insights

Multidrug-resistant Candida auris outbreaks necessitate new diagnostics and treatments. A patent review reveals increasing R&D focus on innovative therapeutic molecules and identification methods to combat this global health threat.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Patent Law

Background:

  • Candida auris is a multidrug-resistant yeast causing global hospital outbreaks.
  • Resistance to major antifungal classes limits treatment options.
  • Difficult identification and environmental persistence contribute to hospital-acquired infections.

Purpose of the Study:

  • To critically review patents for the latest therapeutic and diagnostic advancements against Candida auris.
  • To identify trends in research and development for this emerging pathogen.

Main Methods:

  • A comprehensive patent search was conducted using the Espacenet database.
  • 19 patents were initially identified, with 16 selected for final analysis.
  • Patents were categorized by country, year, and type (treatment or diagnostic).

Main Results:

  • The patent review identified 16 relevant patents concerning Candida auris.
  • A notable increase in patent filings related to new therapeutic molecules and diagnostic methods was observed in recent years.
  • Academic, government, and industry sectors show growing interest in Candida auris R&D.

Conclusions:

  • The patent landscape indicates a significant and growing effort to develop novel solutions for Candida auris.
  • There is a clear trend towards innovation in both antifungal therapies and diagnostic tools.
  • Continued R&D is critical for controlling and preventing Candida auris infections.

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