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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Drugs for Treatment of Constipation-Predominant IBS01:21

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
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Chronic Bowel Disorders: Introduction01:17

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Drugs for Treatment of Diarrhea-Predominant IBS01:17

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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
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A Mouse Model of Intestinal Partial Obstruction
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Floseal-induced small bowel obstruction.

Hamza Ashraf1, Nicholas Low1, Calista Spiro1

  • 1Department of General Surgery, Austin Health, Melbourne, Victoria, Australia.

Journal of Surgical Case Reports
|October 5, 2022
PubMed
Summary

This case report details a rare instance of early small bowel obstruction (SBO) after using Floseal, a hemostatic agent. Surgeons should consider Floseal

Keywords:
Flosealhaemostatic agentlaparoscopic surgerysmall bowel obstruction

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Area of Science:

  • Surgical Innovation
  • Gastroenterology
  • Biomaterials in Surgery

Background:

  • Floseal is a widely used hemostatic agent to enhance natural clotting.
  • Its application in general surgery is common for achieving hemostasis.

Observation:

  • A patient developed early mechanical small bowel obstruction (SBO) post-laparoscopic appendicectomy.
  • Intraoperative findings revealed adhesions involving the Floseal application site on the abdominal wall.

Findings:

  • The study presents the first documented case with intraoperative images of Floseal-associated SBO in over a decade.
  • Adhesions formed around the Floseal application site, causing a mechanical obstruction.

Implications:

  • Floseal may contribute to early post-operative inflammation and adhesion formation.
  • Recommendations include removing excess Floseal and considering it in the differential diagnosis of early SBO.