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Updated: Aug 26, 2025

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Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
Published on: February 18, 2015
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Disseminated Mycoplasma Orale Infection in Patients With Phosphoinositide-3-Kinase Regulatory Subunit 1 Mutations
Arthur H Totten1, Gulbu Uzel2, Pavel P Khil1,2
1Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Open Forum Infectious Diseases
|October 5, 2022
Abstract:
Mycoplasma orale is a rare cause of invasive infection in immunodeficient hosts. Phosphatidylinositol 3-kinase, regulatory subunit 1 (PI3KR1) mutations predispose patients to sinopulmonary infections, alongside bronchiectasis autoimmunity and lymphoproliferation. We report 2 cases of PI3KR1 deficiency with invasive M orale and effective treatment options.
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