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Updated: Aug 26, 2025
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Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
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Transcatheter Atrial Septal Defect Closure Before Versus After Adulthood
Mohamed S Hafez1, Mohamed I Abdelrahman El-Sayed1, Maiy H El Sayed1
1Department of Cardiovascular Medicine, Ain Shams University Hospitals, Cairo, Egypt.
Journal of the Saudi Heart Association
|October 5, 2022
Summary
Early transcatheter closure of atrial septal defects in teenagers leads to better heart function and fewer arrhythmias compared to adult closure. This suggests timely intervention improves long-term cardiac outcomes.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Interventional Cardiology
Background:
- Secundum atrial septal defects (ASD) are congenital heart conditions.
- Transcatheter closure is a common treatment for ASD.
- Long-term outcomes comparing teenage versus adult closure are not well-established.
Purpose of the Study:
- To compare the long-term outcomes of percutaneous transcatheter closure of secundum ASD in teenagers versus adults.
- To assess differences in electrocardiographic and echocardiographic parameters between the two groups.
Main Methods:
- 100 patients with secundum ASD underwent transcatheter closure 2-5 years prior.
- Patients were divided into two groups: teenage (13-19 years) and adult (>30 years) closure.
- Comparison included resting ECG, 24-h Holter ECG, and transthoracic echocardiography.
Main Results:
- Adults showed higher rates of right bundle branch block (69% vs 45%) and arrhythmias like premature atrial contractions (20% vs 6%) and atrial fibrillation (12% vs <1%).
- Adults had significantly larger right ventricular diameter, right atrial area, left atrial volume, and more left ventricular diastolic dysfunction.
- Teenage group exhibited better right ventricular systolic function.
Conclusions:
- Early transcatheter closure of secundum ASD during teenage years results in superior right ventricular systolic function and size.
- Teenage closure is associated with a lower incidence of atrial arrhythmias compared to adult closure.
