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A Case of Thyroid Storm Caused by Thyroiditis.

Katherine Newman1, Leonidas Walthall1

  • 1Medical University of South Carolina, Charleston, USA.

Journal of Investigative Medicine High Impact Case Reports
|October 5, 2022
PubMed
Summary

Thyroid storm, a rare complication of subacute thyroiditis (SAT), involves a dangerous excess of thyroid hormones. This case report details the sixth instance of SAT leading to thyroid storm, highlighting an unusual but severe outcome.

Keywords:
de quervainsubacutethyroid stormthyroiditisthyrotoxicosis

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Area of Science:

  • Endocrinology
  • Internal Medicine
  • Pathophysiology

Background:

  • Thyroid storm is a severe, life-threatening thyrotoxicosis complication characterized by a hyperadrenergic state and cardio-respiratory compromise.
  • Graves disease is the most frequent etiology of thyroid storm.
  • Subacute thyroiditis (SAT) is typically a self-limiting condition involving painful thyroid inflammation, often viral in origin, and commonly presents with transient hyperthyroidism.

Observation:

  • Thyroid storm is an exceptionally rare complication of subacute thyroiditis (SAT).
  • This report documents the sixth known case of SAT associated with thyroid storm.

Findings:

  • The study presents a rare case of thyroid storm occurring in the context of subacute thyroiditis.
  • This finding underscores that while uncommon, SAT can precipitate thyroid storm.

Implications:

  • This case expands the understanding of potential SAT complications beyond transient hyperthyroidism.
  • It emphasizes the need for vigilance in recognizing and managing severe thyrotoxicosis, even in atypical presentations like SAT.
  • Further research may elucidate the specific mechanisms linking SAT to thyroid storm.