Glaucoma in Patients With Endothelial Keratoplasty

Area of Science:

• Ophthalmology
• Corneal Surgery
• Glaucoma Research

Background:

• Endothelial keratoplasty (EK) is the predominant corneal transplant technique in the US.
• Intraocular pressure (IOP) elevation and glaucoma are significant complications following EK, potentially leading to vision loss and graft failure.

Approach:

• This review synthesizes current literature on the incidence, risk factors, and management of IOP elevation and glaucoma post-EK.
• It examines graft outcomes in EK patients with pre-existing or newly developed glaucoma.
• Future research directions for optimizing care are proposed.

Key Points:

• Preoperative factors like high IOP, existing glaucoma, and specific EK indications (e.g., bullous keratopathy) increase glaucoma risk.
• Glaucoma and IOP elevation can negatively impact corneal graft survival after EK.
• Effective management strategies are crucial for preserving vision and graft function.

Conclusions:

• Understanding and addressing glaucoma risk factors are essential for successful EK outcomes.
• Further research is needed to refine clinical protocols for managing glaucoma in EK patients.
• Improved patient care pathways can mitigate vision loss and graft failure in this population.