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Association between multimorbidity, intensive care unit admission, and death in patients with COVID-19 in Brazil: a

Jefferson Paixão Cardoso1, Maria Inês Pardo Calazans2, Aretha Lorena Fonseca Cantanhede Carneiro3

  • 1PhD. Physiotherapist and Full Professor, Department of Health II, Núcleo de Estudos em Saúde da População (NESP), Universidade Estadual do Sudoeste da Bahia (UESB), Jequié (BA), Brazil.

Sao Paulo Medical Journal = Revista Paulista De Medicina
|October 5, 2022
PubMed

Insights

Multimorbidity, the presence of multiple health conditions, significantly impacts intensive care unit (ICU) admissions and deaths among coronavirus disease (COVID-19) patients in Brazil. This study highlights key risk factors associated with these outcomes.

Area of Science:

  • Public Health
  • Epidemiology
  • Infectious Diseases

Background:

  • Multimorbidity is a significant factor influencing outcomes in coronavirus disease (COVID-19) patients.
  • Understanding the relationship between multiple health conditions and severe COVID-19 outcomes is crucial for public health strategies.

Purpose of the Study:

  • To investigate the association between multimorbidity and intensive care unit (ICU) admissions and deaths in COVID-19 patients in Brazil.
  • To identify demographic and clinical factors associated with multimorbidity in severe acute respiratory syndrome (SARS) due to COVID-19.

Main Methods:

  • Cross-sectional study utilizing data from the Influenza Epidemiological Surveillance Information System (SIVEP-Gripe) in Brazil for 2020.
  • Descriptive and stratified analyses were performed on multimorbidity prevalence.
  • Poisson regression was employed to calculate prevalence ratios for associations.

Main Results:

  • Over 671,000 cases of SARS due to COVID-19 were analyzed, with 62.4% exhibiting at least one comorbidity.
  • Multimorbidity was linked to male sex, older age groups (60-70, ≥80 years), non-white skin colors, lower educational attainment, and need for ventilatory support.
  • While all regions and altered CT scans were associated with death, only the Northeast region and higher education correlated with ICU admission.

Conclusions:

  • A clear association exists between multimorbidity, ICU admission, and mortality in COVID-19 patients within the Brazilian context.
  • Findings underscore the importance of considering patient comorbidities in managing severe COVID-19 cases and resource allocation.
Abstract

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