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Vitamin D status-associated postoperative complications in patients with hip dysplasia after periacetabular
Kazuki Kitade1,2, Taro Mawatari1,2, Shoji Baba1
1Department of Orthopaedic Surgery, Hamanomachi Hospital, Fukuoka, Japan.
Insights
Low vitamin D levels are linked to complications after periacetabular osteotomy. Supplementation may help prevent issues like delayed union and stress fractures in patients with low vitamin D status.
Area of Science:
- Orthopedic Surgery
- Endocrinology
- Nutritional Science
Background:
- Periacetabular osteotomy (PAO) is a complex orthopedic procedure.
- Postoperative complications can impact patient outcomes.
- Vitamin D status is crucial for bone healing and overall health.
Purpose of the Study:
- To investigate the association between vitamin D levels and complications following PAO.
- To identify risk factors for delayed union and stress fractures post-PAO.
Main Methods:
- Retrospective review of 46 hips in 39 patients undergoing PAO.
- Assessment of serum 25-hydroxyvitamin D [25(OH)D] levels.
- Evaluation for delayed union of the greater trochanter (DUGT) and ischiopubic stress fractures (IPSFs).
Main Results:
- Mean serum 25(OH)D level was 11.9 ng/ml.
- Prevalence of DUGT was 10.3% and IPSF was 7.7%.
- Low 25(OH)D levels (≤11 ng/ml) and smoking were significantly associated with complications.
Conclusions:
- Severe vitamin D deficiency is common in PAO patients.
- Vitamin D deficiency and smoking are independent risk factors for PAO complications.
- Proactive vitamin D supplementation is recommended for patients with low levels to reduce complications.
Objectives:
This study aimed to clarify the relationship between vitamin D status and complications after periacetabular osteotomy.
Methods:
A total of 46 hips of 39 patients (3 men and 36 women; mean age at surgery, 41.0 years; mean postoperative follow-up duration, 63 months) were reviewed to obtain the following information: patients' serum 25-hydroxyvitamin D [25(OH)D] status, prevalence of postoperative delayed union of osteotomy sites in the greater trochanter (DUGT) and ischiopubic stress fractures (IPSFs), and risk factors.
Results:
The mean serum 25(OH)D level was 11.9 ng/ml. DUGT and IPSF were found in four (10.3%) and three (7.7%) patients, respectively. Serum 25(OH)D levels ≤ 11 ng/ml were significantly associated with DUGT in female patients (p = .02). Serum 25(OH)D levels ≤ 9 ng/ml and smoking were significantly associated with IPSF (p = 0.01 and 0.02, respectively). Overall, 21.7% of patients with serum 25(OH)D levels ≤ 11 ng/ml developed at least one complication; no complications occurred when serum 25(OH)D levels were >11 ng/ml.
Conclusion:
Severe vitamin D deficiency was highly prevalent in relatively young patients. Vitamin D deficiency and smoking were independent risk factors for postoperative complications. Proactive supplementation is advisable to reduce postoperative complications, especially in patients with serum 25(OH)D levels ≤ 11 ng/ml.
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