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Related Concept Videos

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Spindle assembly occurs through three, often coexisting, pathways – the centrosome-mediated pathway, the chromatin-mediated pathway, and the microtubule-mediated pathway – collectively contributing to form a robust spindle apparatus.
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Related Experiment Video

Updated: Aug 26, 2025

Microdissection of Black Widow Spider Silk-producing Glands
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Umbilical spider's web.

S Bourseau1, B Bastens1, P Leclercq1

  • 1Gastroenterology Unit, Clinique Mont Legia, CHC Groupe Santé, Liège, Belgium.

Acta Gastro-Enterologica Belgica
|October 5, 2022
PubMed
Summary
This summary is machine-generated.

Erythema ab igne, a skin condition caused by prolonged heat exposure, presented as a reticular rash on a patient

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Area of Science:

  • Dermatology
  • Internal Medicine
  • Medical Case Reports

Background:

  • Chronic abdominal pain can lead to self-treatment with heat sources.
  • Irritable Bowel Syndrome (IBS) is a common diagnosis associated with chronic abdominal pain.

Observation:

  • A 38-year-old woman presented with chronic abdominal pain and a distinctive reddish, hyperpigmented, reticular skin patch around the umbilicus.
  • Physical examination revealed a non-blanching, reticular, hyperpigmented peri-umbilical skin patch.

Findings:

  • The diagnosis of erythema ab igne was confirmed, linked to the patient's overnight use of hot water bottles for pain relief over three weeks.
  • Erythema ab igne is characterized by a spider's web-like pattern of hyperpigmentation, potentially due to heat-induced vascular damage and hemosiderin deposition.
  • Differential diagnoses for peri-umbilical dermatological signs include caput medusae, Cullen's sign, Walzel's sign, and livedo reticularis.

Implications:

  • This case highlights the importance of considering self-treatment methods when diagnosing skin conditions.
  • Understanding the link between heat exposure and erythema ab igne is crucial for accurate diagnosis and management.
  • Prompt recognition and discontinuation of heat source use typically lead to a benign and self-resolving course for erythema ab igne.