[Invasive fungal infection management in patients with hematological malignancies]

Invasive fungal infections are frequently observed in patients with hematological malignancies. Thus, monitoring the immunosuppressive factors in each patient, such as neutropenia, mucosal injury, steroid consumption, cellular and humoral immunodeficiencies, etc., is important to establish an appropriate antifungal strategy. Additionally, prophylactic approaches should be planned considering the risk of fungal infection, and early clinical tests should be required in patients with persistent fever or other clinical manifestations for the timely diagnosis of invasive fungal infection. Antifungal profile, adverse effects, and clinical purposes, such as prophylaxis, empiric, preemptive, and target therapies, should be considered in antifungal agent selection.