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Updated: Aug 26, 2025

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo
Published on: July 20, 2019
[Hematopoietic regulation and tumor control by the peripheral nervous system]
1Department of Hematology and Oncology, Okayama University Hospital.
Abstract:
The nervous system is distributed throughout all body organs and unconsciously maintains homeostasis. The peripheral nervous system, which comprises autonomic and sensory nerves, is distributed in the bone marrow, which controls hematopoiesis, and the surrounding bone tissue, which is also closely associated with hematopoiesis regulation. Recent advances in research techniques have revealed that the peripheral nervous system affects normal hematopoiesis, hematopoiesis under stress, and the regulation of hematopoietic aging. The peripheral nervous system also affects the development and progression of malignant tumors, including hematopoietic tumors and normal tissue, making the peripheral nerve regulation a potential new therapeutic target.
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