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Updated: Aug 26, 2025

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum
Published on: December 4, 2015
The economic burden of malaria: a systematic review
Mônica V Andrade1, Kenya Noronha1, Bernardo P C Diniz1
1Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Background:
Quantifying disease costs is critical for policymakers to set priorities, allocate resources, select control and prevention strategies, and evaluate the cost-effectiveness of interventions. Although malaria carries a very large disease burden, the availability of comprehensive and comparable estimates of malaria costs across endemic countries is scarce.
Methods:
A literature review to summarize methodologies utilized to estimate malaria treatment costs was conducted to identify gaps in knowledge.
Results:
Only 45 publications met the inclusion criteria. They utilize different methods, include distinct cost components, have varied geographical coverage (a country vs a city), include different periods in the analysis, and focus on specific parasite types or population groups (e.g., pregnant women).
Conclusions:
Cost estimates currently available are not comparable, hindering broad statements on the costs of malaria, and constraining advocacy efforts towards investment in malaria control and elimination, particularly with the finance and development sectors of the government.

