Improved Outcomes With Transradial Approach in Alcohol Septal Ablation
Noah Blaker, Katrina Bidwell, Ahmadreza Karimianpour
1Division of Cardiology, Department of Medicine, Medical University of South Carolina, 114 Doughty Street, MSC 592, Charleston, SC 29464 USA. fernandv@musc.edu.
The Journal of Invasive Cardiology
|October 6, 2022
Summary
The transradial approach for alcohol septal ablation (ASA) is as effective as the transfemoral approach, with lower contrast use and fewer complications. This study compared outcomes of transradial vs. transfemoral ASA in 274 patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Surgery
Background:
- Transradial cardiac catheterization is known for fewer vascular complications compared to the transfemoral approach.
- Limited data exists on the biradial approach for alcohol septal ablation (ASA).
Purpose of the Study:
- To compare procedural outcomes of transradial versus traditional transfemoral approaches in ASA.
- To evaluate efficacy and safety differences between the two methods for ASA.
Main Methods:
- Retrospective analysis of 274 consecutive patients undergoing ASA.
- Patients were divided into transradial (137) and transfemoral (137) subgroups.
- Comparison of procedural success, LVOT gradient reduction, contrast volume, fluoroscopy time, and complications.
Main Results:
- No significant difference in left ventricular outflow tract gradient (LVOTG) reduction between groups.
- Transradial approach used significantly less contrast volume (98 mL vs. 111 mL).
- Transradial approach had a lower incidence of complications (0.13 vs. 0.23) but higher fluoroscopy time.
Conclusions:
- Alcohol septal ablation via the transradial approach is equally effective as the transfemoral approach.
- The transradial method is associated with significantly reduced contrast usage and fewer complications.
- The transradial approach offers a safer alternative for ASA compared to the traditional transfemoral route.


