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The Great Masquerader: Coronary Occlusion From Thrombus in Ascending Aortic Aneurysm Causing Anterior-Wall STEMI With
Wiwat Kanjanarutjawiwat1, Sarunpong Pibalyart, Paruepong Makarasen
1Cardiology Unit, Department of Internal Medicine, Phrapokklao Hospital Chanthaburi, 38 Leabnean Road, Chanthaburi, Thailand 22000. mdwiwat@gmail.com.
Insights
A rare case of syphilitic aortitis led to a large thrombus in the ascending aorta, causing myocardial infarction and death. Early recognition of syphilitic aortic aneurysms is crucial for preventing such fatal outcomes.
Area of Science:
- Cardiovascular Medicine
- Infectious Diseases
- Pathology
Background:
- Tertiary syphilis is a rare condition in modern medicine.
- Syphilitic aortitis can lead to ascending aortic aneurysms.
Observation:
- A 55-year-old man presented with chest pain due to a thrombus in the ascending aorta.
- The thrombus occluded the left coronary artery ostia, causing myocardial infarction.
Findings:
- Autopsy revealed an ascending aortic aneurysm with syphilitic aortitis.
- Atherosclerosis with ulcerative plaque and endarteritis were noted.
- A large mobile thrombus was found in the left coronary cusp, extending into the aorta.
Implications:
- This case highlights a rare cause of ST-elevation myocardial infarction.
- Early diagnosis of syphilitic aortic aneurysms is critical for preventing coronary artery complications.
- Recognizing thrombus formation in syphilitic aortic aneurysms is key to timely intervention.
Abstract:
A 55-year-old man with history of alcoholism presented to our hospital complaining of severe substernal chest pain. After a series of tests and procedures, a large mobile thrombus occupying the left coronary cusp with extension into the ascending aorta was discovered. The patient's hemodynamics remained unstable. After 6 hours of resuscitation, his hemodynamics could not be maintained and eventually, he expired. The autopsy result revealed an ascending aortic aneurysm with atheromatous plaques and focal ulceration without thrombus in the aneurysm. The pathological report showed evidence of acute anterior myocardial infarction, aneurysm with endarteritis and plasma cell infiltration, as well as atherosclerosis with ulcerative plaque. These findings were compatible with syphilitic aortitis. Tertiary syphilis is rarely encountered in current medical practice. Thrombus in the ascending aorta occluding the left coronary artery ostia and resulting in coronary embolus into the left anterior descending is a rare cause of acute anterior ST-segment-elevation myocardial infarction. The combination of these rare causes raises special attention to early recognition of thrombus forming from the syphilitic aortic aneurysm in the ascending aorta propagating to the coronary artery as a cause of myocardial infarction.
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