First-use syndrome in patients treated with hollow-fiber dialyzers

A 2-year survey on first-use syndrome (FUS) in hemodialysis showed that there were an average of 181 FUS reactions per year. Nearly 39% of the patients who experienced a FUS reaction had experienced previous FUS reactions. No correlation was found between the frequency of FUS reactions and the sex of the patient, however, a strong correlation was found with respect to the age and race of the patients. The fact that a patient recently started dialysis treatment or has been treated with dialysis for some time appears to have no bearing in the risk of experiencing a FUS reaction.