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Chorio-meningo-encephalitis due to Listeria monocytogenes after renal transplantation
The Japanese Journal of Experimental Medicine
|April 1, 1978
Abstract:
A 35-year-old man, who underwent renal transplantation, died of meningo-encephalitis with symptoms of meningitis for only 8 days. The autopsy revealed marked chorio-meningo-encephalitis caused by Listeria monocytogenes. This report on listeriosis in renal transplant patients is the second in our country, where adult cases of listeriosis are rare. Recent knowledge about listeriosis in renal transplants is reviewed and discussed.
Insights
A renal transplant patient died from Listeria monocytogenes meningo-encephalitis. This rare adult listeriosis case highlights infection risks in immunocompromised individuals post-transplant.
Area of Science:
- Infectious Diseases
- Nephrology
- Immunology
Background:
- Renal transplantation is a life-saving procedure for end-stage renal disease.
- Immunosuppression is essential post-transplantation, increasing susceptibility to opportunistic infections.
- Listeriosis, caused by Listeria monocytogenes, is a serious infection, particularly in immunocompromised hosts.
Observation:
- A 35-year-old male renal transplant recipient presented with acute meningo-encephalitis symptoms.
- The patient's illness progressed rapidly over 8 days, leading to death.
- Autopsy confirmed severe chorio-meningo-encephalitis attributed to Listeria monocytogenes infection.
Findings:
- The case represents a rare instance of adult listeriosis in the country.
- Listeria monocytogenes was identified as the causative agent of the fatal meningo-encephalitis.
- The clinical presentation and autopsy findings underscore the aggressive nature of listeriosis in this context.
Implications:
- This case highlights the critical need for vigilance regarding listeriosis in renal transplant recipients.
- Early diagnosis and prompt treatment are crucial for improving outcomes in transplant-associated listeriosis.
- Further research into preventative strategies and management protocols for listeriosis in immunocompromised populations is warranted.