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Updated: Aug 26, 2025

Applying Microfluidics to Electrophysiology
Published on: October 1, 2007
Microdosing: Old Wine in a New Bottle? Current State of Affairs and Future Avenues
José Afonso1, Fábio Yuzo Nakamura2, Ivan Baptista1,3
1Faculty of Sport, Center of Research, Education, Innovation, and Intervention in Sport (CIFI2D), University of Porto, Porto,Portugal.
Purpose:
Microdosing of exercise aims to deliver smaller daily training doses but at a higher weekly frequency, adding up to a similar weekly volume as in nonmicrodosed training. This commentary critically discusses this concept, which appears to be a rebranding of the "old" distributed practice of motor learning.
Development:
We propose that microdosing should relate to the minimal dose that develops or at least maintains the selected capacities or skills as this training dose matters to practitioners, especially during the in-season period. Moreover, microdosing has been applied mainly to develop strength and endurance, but abilities such as sprinting and changing direction could also be microdosed, as well as technical-tactical skills.
Conclusions:
The concept of microdosing should be reframed to avoid redundancy with the concept of distributed practice while providing valuable information concerning the minimum doses that still generate the intended effects and the thresholds that determine whether a dose is "micro" or not.
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