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Related Concept Videos

Obesity01:24

Obesity

585
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
585
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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Related Experiment Video

Updated: Aug 26, 2025

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

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Precision Medicine for Obesity.

Lizeth Cifuentes1, Maria Daniela Hurtado A1,2, Jeanette Eckel-Passow3

  • 1Precision Medicine for Obesity Program, Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.

Digestive Disease Interventions
|October 7, 2022
PubMed
Summary
This summary is machine-generated.

Precision medicine offers a personalized approach to obesity treatment by utilizing high-throughput technologies and biological markers. This strategy aims to improve weight loss effectiveness and safety by accounting for individual patient differences.

Keywords:
ADOPTgeneticsmicrobiomephenotypes

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Area of Science:

  • Metabolic disease research
  • Biochemistry
  • Genomics and personalized medicine

Background:

  • Obesity is a complex, multifactorial disease with limited success in current treatments.
  • Human heterogeneity necessitates personalized approaches for effective disease management.
  • High-throughput biochemical assays are advancing the understanding of obesity's pathophysiology.

Purpose of the Study:

  • To review the application of high-throughput technologies in precision obesity medicine.
  • To explore the potential of biological markers for personalized obesity treatment strategies.
  • To provide a perspective on the current state and future of precision obesity care.

Main Methods:

  • Literature review of high-throughput technologies and their application to obesity.
  • Analysis of biological markers derived from biochemical assays.
  • Examination of precision medicine principles in the context of obesity.

Main Results:

  • High-throughput technologies are characterizing obesity pathophysiology and identifying key factors.
  • Biological markers are emerging for personalized treatment development.
  • Significant progress has been made, but challenges remain for widespread clinical adoption.

Conclusions:

  • Precision medicine holds promise for improving obesity treatment outcomes.
  • Further research and technological integration are needed to realize the full potential of precision obesity medicine.
  • Personalized treatment strategies are crucial for maximizing effectiveness, tolerability, and safety in obesity management.