[Lysosomal enzymes in lymphocytes in experimental lymphatic leukemia in mice]

The activity of lysosomatic enzymes, i.e.: alkaline phosphatase, beta-glucoronidase, lysozyme and non-specific alfa-esterase in the organic lymphocytes and in the lymphocytes of peripheral blood were determined. It was found that the disorders of intracellular distribution of enzymes are the evidence of destabilization of lysozymes membrane with the following translocation of alkaline hydrolases into cytoplasm. There were observed the debilitation of the protective possibilities and the decrease of unspecific immunological resistance of leukaemia lymphocytes.