Neodymium-YAG transscleral cyclocoagulation in rabbit eyes

Area of Science:

• Ophthalmology
• Medical Laser Technology

Background:

• Transscleral ruby cyclocoagulation is an established method for reducing intraocular pressure.
• The development of Nd-YAG lasers with a thermal mode presents a potential alternative for cyclocoagulation procedures.

Purpose of the Study:

• To evaluate the efficacy and safety of Nd-YAG laser thermal mode for reducing intraocular pressure.
• To assess the long-term effects of this treatment on ocular tissues.

Main Methods:

• Seven pigmented rabbits underwent unilateral treatment of one eye using the thermal mode of an Nd-YAG laser.
• Intraocular pressure was monitored for three months post-treatment.
• Histopathological examination of ocular tissues was performed.

Main Results:

• Treated eyes exhibited significantly lower intraocular pressure compared to untreated contralateral eyes (p < 0.001).
• The reduction in intraocular pressure was sustained throughout the three-month study period.
• Pathological findings showed selective destruction of ciliary processes with preservation of surrounding tissues.

Conclusions:

• Nd-YAG laser thermal mode is a safe and effective method for lowering intraocular pressure.
• This technique offers a promising therapeutic option for managing glaucoma.
• Selective ciliary process ablation with minimal collateral damage is achievable.