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Related Concept Videos

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Related Experiment Video

Updated: Aug 26, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Focus stacking in non-contact dermoscopy.

Lennart Jütte1, Zhiyao Yang1, Gaurav Sharma1

  • 1Leibniz University Hannover, Hannover Centre for Optical Technologies, Hannover, Germany.

Biomedical Physics & Engineering Express
|October 7, 2022
PubMed
Summary
This summary is machine-generated.

This study introduces a focus stacking technique for non-contact dermoscopy, improving skin cancer detection. The method generates all-in-focus images and extracts topographical data for enhanced dermatological analysis.

Keywords:
dermatologydermoscopyfocus stackingmelanomaskinskin cancer imaging

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Area of Science:

  • Dermatology
  • Medical Imaging
  • Optical Engineering

Background:

  • Dermoscopy is crucial for early skin cancer detection.
  • Non-contact dermoscopes often produce images with limited depth of field, resulting in out-of-focus areas.
  • This limitation hinders detailed topographical analysis of skin lesions.

Purpose of the Study:

  • To develop an easy-to-implement focus stacking approach for non-contact dermoscopy.
  • To achieve all-in-focus images of skin topography.
  • To extract additional topographical information from image stacks.

Main Methods:

  • Implemented a focus stacking procedure using a non-contact dermoscope with an electrically tunable liquid lens.
  • Developed software for raw image data acquisition and processing.
  • Generated high-resolution, hyper-resolution dermoscopic images.

Main Results:

  • Demonstrated the feasibility of all-in-focus imaging in non-contact dermoscopy.
  • Successfully extracted topographical information from acquired image stacks.
  • Created a system capable of producing high-resolution, hyper-resolution dermoscopic images.

Conclusions:

  • The focus stacking approach enhances non-contact dermoscopic examination.
  • This method aids in the early detection of skin diseases like cancer by providing hyperfocus images and topographical data.
  • Future clinical application for skin cancer diagnostics and inflammatory skin disease imaging is planned.