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Related Concept Videos

Uncertainty: Overview00:59

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In analytical chemistry, we often perform repetitive measurements to detect and minimize inaccuracies caused by both determinate and indeterminate errors. Despite the cares we take, the presence of random errors means that repeated measurements almost never have exactly the same magnitude. The collective difference between these measurements - observed values - and the estimated or expected value is called uncertainty. Uncertainty is conventionally written after the estimated or expected value.
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Related Experiment Video

Updated: Aug 26, 2025

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Uncertainty modulates visual maps during noninstrumental information demand.

Yvonne Li1,2, Nabil Daddaoua1,2, Mattias Horan1

  • 1Department of Neuroscience, Columbia University, New York, NY, USA.

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|October 7, 2022
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Summary
This summary is machine-generated.

Animals seek information driven by uncertainty and positive outcomes. Parietal cortex activity reflects this, with uncertainty signaling linked to behavior, suggesting distinct neural pathways for information seeking.

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Area of Science:

  • Neuroscience
  • Cognitive Science
  • Animal Behavior

Background:

  • Animals possess intrinsic motivation to acquire information, independent of external rewards.
  • This motivation is driven by the need to reduce uncertainty and seek positive outcomes.

Purpose of the Study:

  • To investigate the neural mechanisms underlying intrinsic information-seeking behavior.
  • To examine the role of the parietal cortex in processing uncertainty and valence during information acquisition.

Main Methods:

  • Recorded neural activity in the parietal cortex of monkeys performing an information-seeking task.
  • Monkeys were free to obtain information about probabilistic rewards without explicit training.

Main Results:

  • Parietal neuronal activity was independently modulated by both reward valence and uncertainty.
  • Uncertainty-related neural enhancement, but not valence-related enhancement, consistently correlated with behavioral sensitivity.
  • Findings suggest distinct neural pathways for uncertainty-driven and valence-driven information demand.

Conclusions:

  • The parietal cortex plays a crucial role in processing uncertainty during intrinsic information seeking.
  • Valence-driven information seeking may involve additional downstream neural mechanisms beyond the parietal cortex.