Related Experiment Video
Updated: Aug 26, 2025

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
Published on: November 10, 2017
[Chinese expert consensus on management of dyslipidemia in the elderly]
1Department of Geriatrics, Peking University First Hospital, Beijing 100034, China.
Insights
This expert consensus addresses dyslipidemia management in Chinese elderly, focusing on safe lipid-lowering drug use to prevent atherosclerotic cardiovascular disease (ASCVD) and reduce cardiovascular events.
Area of Science:
- Cardiology
- Geriatrics
- Pharmacology
Background:
- Dyslipidemia is a key risk factor for atherosclerotic cardiovascular disease (ASCVD).
- Statins are effective in preventing ASCVD events but are underutilized in the elderly due to safety concerns.
- High withdrawal rates of lipid-lowering agents are observed in older populations.
Purpose of the Study:
- To provide guidance on managing dyslipidemia in Chinese elderly patients.
- To promote the effective and safe use of lipid-lowering drugs in this demographic.
- To address the challenges of insufficient drug use and high withdrawal rates.
Main Methods:
- Review of clinical evidence on lipid-lowering drug use in the elderly.
- Analysis of domestic and international lipid management guidelines.
- Consensus development by experts in geriatrics and cardiology.
Main Results:
- Identification of specific challenges in lipid management for Chinese elderly.
- Recommendations for optimizing statin therapy and other lipid-lowering agents.
- Strategies to improve adherence and reduce drug withdrawal.
Conclusions:
- Effective management of dyslipidemia is crucial for preventing ASCVD in Chinese elderly.
- This consensus provides evidence-based recommendations for safe and effective lipid-lowering therapy.
- Addressing safety concerns and adherence is vital for improving cardiovascular outcomes.
Abstract:
Dyslipidemia is an important risk factor of atherosclerotic cardiovascular disease (ASCVD). Statins delay the occurrence and development of ASCVD, and reduce the risk of cardiovascular events and death. Due to safety concerns, there exist insufficient use of lipid-lowering agents and a high withdrawal rate of the agents in the elderly. To promote the prevention and treatment of ASCVD, this expert consensus is issued and focuses on the management of dyslipidemia of Chinese elderly basing on the clinical evidence of the use of lipid-lowering drugs by the elderly, and the lipid management guidelines and expert consensus recommendations at home and abroad.
Related Concept Videos
Atherosclerosis III: Management
Coronary Artery Disease IV: Preventive Measures
Lipids: Dietary Sources and Requirements
Angina IV: Management
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...

