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Updated: Aug 26, 2025

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Osteochondritis Dissecans of the Knee in Young Athletes
Michael M Chau1, Marc A Tompkins2
1Department of Orthopedic Surgery, University of Minnesota, 2450 Riverside Avenue South Suite R200, Minneapolis, MN 55454, USA.
Abstract:
Osteochondritis dissecans of the knee is a relatively rare disorder in young athletes that can lead to premature osteoarthritis. It may be caused by multiple factors, including repetitive stress, local ischemia, aberrant endochondral ossification of the subarticular physis, and hereditary disposition. Nonoperative treatment is typically attempted for patients with open physes, stable lesions, and minimal symptoms. Operative treatment is offered to patients with closed physes, unstable lesions, mechanical symptoms, and failure of nonoperative treatment. Customized rehabilitation and return to sport programs are important for successful outcomes regardless of treatment type.
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