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Updated: Aug 26, 2025

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
Published on: May 27, 2016
Infrared Thermometry for Acute Radiation Syndrome in Mice
Yu A Zrilova1, T M Bychkova2,3, Т А Karaulova2
1Burnasyan Federal Medical Biophysical Centre, Federal Medical Biological Agency of Russia, Moscow, Russia. uzrilova@gmail.com.
Abstract:
Experiment on female ICR CD-1 mice showed that non-contact infrared thermometry can be used for short-term and medium-term prognosis of animal death during the development of acute radiation syndrome. In mice irradiated with X-rays in a dose of 7.25 Gy (LD100/30), the body temperature 1 and 5 days before death was below the normal limit (<36.4°C) in 90 and 50% cases, respectively. The decrease in body temperature closely correlated with a decrease in the mean body weight in irradiated animals (from 24 to 19 g).

