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Related Experiment Video

Updated: Aug 26, 2025

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

Thyroid and renal cancers: A bidirectional association.

Maria Irene Bellini¹, Eleonora Lori¹, Flavio Forte²

¹Department of Surgical Sciences, Sapienza University of Rome, Rome, Italy.

Frontiers in Oncology

|October 10, 2022

Summary

This summary is machine-generated.

Thyroid and kidney cancers are linked, with thyroid cancer increasing kidney cancer risk. Early detection and treatment are crucial for improved survival rates in patients with these interconnected malignancies.

Keywords:

cancer risk cancer surveillance and screening multiple cancer renal cancer thyroid cancer

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Published on: April 17, 2013

Area of Science:

Oncology
Endocrinology
Nephrology

Background:

Thyroid and kidney health are deeply interconnected, with dysfunction in one affecting the other.
Cancer is increasingly recognized as a systemic disease, with rising thyroid tumor incidence and links to kidney disease.
Public health awareness is needed due to the association between various cancers and increased kidney disease risk.

Approach:

A systematic review analyzed 18 studies on the bidirectional relationship between thyroid and renal cancers.
Data on patient characteristics, histology, time to secondary malignancy, treatment, and follow-up were compiled.
A total of 776 patients were included, with a median age of 64 years.

Key Points:

Obesity and family history were common risk factors; genetic susceptibility, like Cowden syndrome, was suggested.
Men showed a higher likelihood of developing kidney cancer after thyroid cancer (54%).
The median time to secondary kidney malignancy was 5.2 years post-thyroid cancer diagnosis.

Conclusions:

Improved thyroid cancer prognosis has led to a rise in secondary malignancies, particularly kidney cancer.
Early detection through surveillance allows for radical treatment and disease-free survival.
The interplay between thyroid and kidney cancers necessitates ongoing research and clinical attention.